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Taking Ohtuvayre

Ohtuvayre is taken through a nebulizer
twice a day

Never used a nebulizer before?
No problem.

Treatments that use a nebulizer are fairly common in COPD, and your healthcare provider will be able to answer any questions you have about how to use one.

Here are some of the important details you should know before using Ohtuvayre:

This treatment can only be inhaled through a nebulizer mouthpiece—there's no other way to take it

You cannot mix other medicines with Ohtuvayre in your nebulizer

Each Ohtuvayre dose comes in an ampule (a small sealed vial) that is sealed in a foil pouch—don’t open it until you are ready to use a dose, and when you have opened it, use Ohtuvayre right away

Preparing to Use Ohtuvayre

Make sure you know how to use your nebulizer machine before using your first dose of Ohtuvayre.

Download and read the following directions before using Ohtuvayre. If you have any questions, ask your healthcare provider or pharmacist.

Frequently
Asked
Questions
Ohtuvayre is inhaled twice daily, one dose in the morning and one dose in the evening. Each dose should take about 5 to 7 minutes.
No. Ohtuvayre is only to be administered through a standard jet nebulizer with a mouthpiece connected to an air compressor. For proper administration, please refer to the Ohtuvayre Instructions for Use.
No, do not mix other medicines with Ohtuvayre in your nebulizer and take it exactly as prescribed.

How often should Ohtuvayre be taken?

Twice daily—once in the morning and once in the evening

  • Do not use more than 1 dose of Ohtuvayre in a single treatment.
  • Do not use more than 2 doses a day.

Do not use more than 1 ampule of Ohtuvayre in a single treatment.

Do not use more than 2 ampules a day.

5-7 minute sessions*

*Treatment time is dependent on your individual nebulizer.

Ohtuvayre offers a first-of-its-kind way to treat your COPD.

Find out how Ohtuvayre works differently.

Reclaim your breath

You’ve seen how it works—now see what Ohtuvayre can do.

Do not use Ohtuvayre to treat sudden breathing problems. Always have a rescue inhaler with you.

Who Should Not use Ohtuvayre?

Do not use Ohtuvayre if you have had an allergic reaction to ensifentrine or any of the ingredients in Ohtuvayre.

What should I tell my healthcare provider before using Ohtuvayre?

Before you use Ohtuvayre, tell your healthcare professional if you have or have had a history of mental health problems including depression and suicidal behavior; have liver problems; are pregnant or plan to become pregnant; are breastfeeding. It is not known if Ohtuvayre may harm your unborn baby. It is not known if the medicine in Ohtuvayre passes into your breast milk and if it can harm your baby.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the most common side effects of Ohtuvayre?

The most common side effects of Ohtuvayre include back pain, high blood pressure, bladder infection and diarrhea.

These are not all the possible side effects of Ohtuvayre. Call your doctor for medical advice about side effects. You may report side effects to FDA at
1-800-FDA-1088.

This summary does not include all the information about Ohtuvayre and is not meant to take the place of a discussion with your healthcare provider about your treatment.

For further information, please see the Full Prescribing Information, including the Patient Information Leaflet.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.