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WHAT CAN OHTUVAYRE OFFER?

Better breathing on day one. Relief that lasts.
That’s feeling lighter with Ohtuvayre.

Ohtuvayre delivers:

Better breathing

Patients using Ohtuvayre experienced significant improvements in lung function.

Symptom improvement

Ohtuvayre is used to improve symptoms of COPD for better breathing.

Lightness that lasts

Patients experienced better breathing within the first day of using Ohtuvayre—an effect that was seen to last for the full 24 weeks that Ohtuvayre was studied.

Ohtuvayre works on its own or with other treatments.

Already using another treatment for COPD? That's alright— your healthcare provider can add Ohtuvayre to your current treatment plan.

Frequently
Asked
Questions
Yes, Ohtuvayre can be taken if you are currently on other COPD treatments.
Do not stop taking Ohtuvayre even if you are feeling better, unless your healthcare provider tells you to.
Unlike rescue inhaler medications, which are taken to relieve sudden symptoms, Ohtuvayre is a maintenance therapy designed to be taken in regular, twice daily treatments. For the best results, take Ohtuvayre exactly as prescribed by your healthcare provider and refer to your nebulizer’s instruction manual.

Ohtuvayre is also well tolerated.

See the safety information and side effects of Ohtuvayre.

Using a Nebulizer to Take Ohtuvayre

Ohtuvayre works differently than other treatments, and it’s taken through a nebulizer—a common delivery method in COPD.

Do not use Ohtuvayre to treat sudden breathing problems. Always have a rescue inhaler with you.

Who Should Not use Ohtuvayre?

Do not use Ohtuvayre if you have had an allergic reaction to ensifentrine or any of the ingredients in Ohtuvayre.

What should I tell my healthcare provider before using Ohtuvayre?

Before you use Ohtuvayre, tell your healthcare professional if you have or have had a history of mental health problems including depression and suicidal behavior; have liver problems; are pregnant or plan to become pregnant; are breastfeeding. It is not known if Ohtuvayre may harm your unborn baby. It is not known if the medicine in Ohtuvayre passes into your breast milk and if it can harm your baby.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the most common side effects of Ohtuvayre?

The most common side effects of Ohtuvayre include back pain, high blood pressure, bladder infection and diarrhea.

These are not all the possible side effects of Ohtuvayre. Call your doctor for medical advice about side effects. You may report side effects to FDA at
1-800-FDA-1088.

This summary does not include all the information about Ohtuvayre and is not meant to take the place of a discussion with your healthcare provider about your treatment.

For further information, please see the Full Prescribing Information, including the Patient Information Leaflet.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.