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What is Ohtuvayre?

The first of its kind:
Ohtuvayre works differently.

Discover a unique, steroid-free approach to
COPD treatment in adults.

Ohtuvayre is used to improve the symptoms of COPD for better breathing.

Ohtuvayre is an inhaled medicine that works differently by decreasing the activity of two enzymes called PDE3 and PDE4.

In doing so, it can lead to relaxation of your airway muscles and reduce inflammation—helping you to reclaim your breath.

Getting started with Ohtuvayre

Once you and your healthcare provider decide you’re a good fit for treatment with Ohtuvayre, our Verona Pathway Plus team helps you get on and stay on treatment. The prescription is sent directly to our team to help navigate insurance coverage, financial support and our Specialty Pharmacy network for delivery to your door.

1 Complete the
Enrollment Form
2 Talk to a Verona Pathway Plus Care Coordinator
3 Schedule delivery from our Specialty Pharmacy

Learn more about how Verona Pathway Plus can help.

Frequently
Asked
Questions
Ohtuvayre works differently—without the use of steroids. It helps the muscles around the airways in your lungs stay relaxed. It also helps to decrease inflammation in the lungs to reduce breathing problems.
Ohtuvayre was proven safe and well-tolerated in clinical trials. See Ohtuvayre Safety for more detailed information.
Ohtuvayre can be used with any standard jet nebulizer with a mouthpiece. When you speak with the Specialty Pharmacy about your prescription shipment, they also can help you get a nebulizer and supplies, or will let you know if you can use a nebulizer that you already have.

Reclaim your breath

You’ve seen how it works—now see what Ohtuvayre can do.

Using a Nebulizer to Take Ohtuvayre

Ohtuvayre works differently than other treatments and it’s taken through a nebulizer—a
common delivery method in COPD.

Do not use Ohtuvayre to treat sudden breathing problems. Always have a rescue inhaler with you.

Who Should Not use Ohtuvayre?

Do not use Ohtuvayre if you have had an allergic reaction to ensifentrine or any of the ingredients in Ohtuvayre.

What should I tell my healthcare provider before using Ohtuvayre?

Before you use Ohtuvayre, tell your healthcare professional if you have or have had a history of mental health problems including depression and suicidal behavior; have liver problems; are pregnant or plan to become pregnant; are breastfeeding. It is not known if Ohtuvayre may harm your unborn baby. It is not known if the medicine in Ohtuvayre passes into your breast milk and if it can harm your baby.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the most common side effects of Ohtuvayre?

The most common side effects of Ohtuvayre include back pain, high blood pressure, bladder infection and diarrhea.

These are not all the possible side effects of Ohtuvayre. Call your doctor for medical advice about side effects. You may report side effects to FDA at
1-800-FDA-1088.

This summary does not include all the information about Ohtuvayre and is not meant to take the place of a discussion with your healthcare provider about your treatment.

For further information, please see the Full Prescribing Information, including the Patient Information Leaflet.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.